TORONTO, ONTARIO–(Marketwired – April 3, 2013) – Arch Biopartners Inc (“Arch” or the “Company”) (CNSX:ACH)(OTCBB:FOIFF) today announced that Arch scientists have co-authored a paper disclosing findings that links inflammatory bowel disease (“IBD”) to caspase 1, a key enzyme that regulates inflammation and cell homeostasis in the gut.
The Arch scientists are using these novel findings to develop new diagnostic tests to monitor IBD activity, response to treatment and to differentiate IBD from conditions such as irritable bowel syndrome (“IBS”).
University of Alberta scientist Dr. Julia Liu and Arch scientists Dr. Randall Irvin, Dr. Daniel Muruve and Dr. Elisabeth Davis are among the co-authors of a paper published in the journal Inflammatory Bowel Diseases titled “Epithelial Cell Extrusion Leads to Breaches in the Intestinal Epithelium” and can be accessed at:
In their publication, the investigators show that inflammatory enzyme activation in intestinal epithelial cells leads to changes in intestinal epithelium integrity and increased intestinal permeability, a central feature of IBD.
About IBD and IBS
IBD is a chronic disorder of the gastrointestinal tract, including Crohn’s disease or ulcerative colitis, characterized by inflammation of the intestine and resulting in abdominal cramping and persistent diarrhea. According to the Crohn’s and Colitis Foundation, approximately 1.4M Americans suffer from IBD. Current methods used to diagnose IBD include endoscopy, pill endoscopy and CT scans.
IBS is a condition of the bowel that also causes frequent abdominal discomfort, pain and diarrhea. IBS affects approximately 10% of the world’s population and there is no readily available diagnostic test for IBS. Doctors generally perform a battery of tests to exclude all other causes of abdominal discomfort before giving the clinical diagnosis of IBS.
As a result, a common clinical problem is the inability to easily differentiate IBD from IBS. In addition, there is no generally accepted, objective method for monitoring IBD and the effectiveness of its treatment.
About Arch Biopartners
Arch Biopartners is a portfolio based technology company established to develop new products and technology for sale to pharmaceutical and industrial companies.
For more information on the Company, please consult the other public documents filed on SEDAR at www.sedar.com.
The Company’s website address is: www.archbiopartners.com.
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