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Gamma-secretase represents a therapeutic target for the treatment of invasive glioma mediated by the p75 neurotrophin receptor. PLoS Biol. 2008 Nov 25;6(11):e289. PubMed PMID: 19067488; PubMed Central PMCID: PMC2586378.
Wang L, Rahn JJ, Lun X, Sun B, Kelly JJ, Weiss S, Robbins SM, Forsyth PA, Senger DL.
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The Pseudomonas aeruginosa type IV pilin receptor binding domain functions as an adhesin for both biotic and abiotic surfaces. Mol Microbiol. 2006 Feb;59(4):1083-96. Erratum in: Mol Microbiol. 2006 May;60(3):813. PubMed PMID: 16430686.
Giltner CL, van Schaik EJ, Audette GF, Kao D, Hodges RS, Hassett DJ, Irvin RT.
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A peptide - stainless steel reaction that yields a new bioorganic - metal state of matter. Biomaterials. 2011 Aug;32(23):5311-9. Epub 2011 May 7. PubMed PMID: 21550656.
Davis EM, Li DY, Irvin RT.
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NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis.
Inflamm Bowel Dis. 2011 Jun;17(6):1359-72. doi: 10.1002/ibd.21478. Epub 2010 Sep 24. PubMed PMID: 20872834; PubMed Central PMCID:PMC3026862.
Hirota SA, Ng J, Lueng A, Khajah M, Parhar K, Li Y, Lam V, Potentier MS, Ng K, Bawa M, McCafferty DM, Rioux KP, Ghosh S, Xavier RJ, Colgan SP, Tschopp J, Muruve D, Macdonald JA, Beck PL. |
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The NLRP3 inflammasome promotes renal inflammation and contributes to CKD.
J Am Soc Nephrol. 2010 Oct;21(10):1732-44. Epub 2010 Aug 5. PubMed PMID: 20688930; PubMed Central PMCID:PMC3013544.
Vilaysane A, Chun J, Seamone ME, Wang W, Chin R, Hirota S, Li Y, Clark SA, Tschopp J, Trpkov K, Hemmelgarn BR, Beck PL, Muruve DA. |
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Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome.
Gastroenterology. 2010 Aug;139(2):542-52, 552.e1-3. Epub 2010 Apr 13. PubMed PMID: 20398664.
Ng J, Hirota SA, Gross O, Li Y, Ulke-Lemee A, Potentier MS, Schenck LP, Vilaysane A, Seamone ME, Feng H, Armstrong GD, Tschopp J, Macdonald JA, Muruve DA, Beck PL. |
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