Arch Biopartners Enters Agreement to Develop Prototype Diagnostic Imaging Agents for Brain Tumor Stem Cells
TORONTO, ONTARIO--(Marketwire - June 27, 2011) - Arch Biopartners Inc ("Arch" or the "Company") (CNSX:ACH)(OTC:FOIFF) and its subsidiary Arch Cancer Therapeutics ("ACT") today announced ACT has entered into an Agreement for Research Services (the "Agreement") with the National Research Council of Canada (NRC).
Under the agreement, the NRC will combine ACT's brain tumor initiating cell (BTIC)-targeting peptide technology with paramagnetic nanoparticles to develop prototype BTIC diagnostic imaging agents for use in magnetic resonance imaging ("MRI").
BTICs are a cancer stem cell population that represent a significant disease reservoir believed to play an important role in the formation and recurrence of malignant glioma in humans. BTICs are not detected by current medical diagnostic imaging technologies.
Paramagnetic nanoparticles are small injectable particles used for molecular imaging and can be visualized by MRI. It is anticipated the combination of ACT's BTIC targeting peptides and paramagnetic nanoparticles will for the first time make BTICs visible.
It is expected that this development contract, including animal in vivo testing, will be completed within nine months, and if successful, will further validate ACT's BTIC-targeting technology as a potential diagnostic tool for human malignant glioma.
About Arch Cancer Therapeutics
ACT is an Alberta corporation wholly owned by Arch Biopartners. ACT's objective is to develop non-invasive diagnostic and therapeutic molecules for brain cancer utilizing new and innovative approaches.
Despite intensive research over the past 30 years, clinical outcomes for patients with malignant glioma have not changed substantially with average survival rates remaining at a dismal 12-15 months. ACT's proprietary molecules are specialized peptides that identify and target brain tumor initiating cells ("BTIC") and invasive brain cancer cells, two disease reservoirs that are not normally seen using current state of the art diagnostic imaging techniques.
About Arch Biopartners
Arch Biopartners is a portfolio based biotechnology company established to developing early stage proprietary technology for sale to pharmaceutical and industrial companies.
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